Başkanın hayatını mal olan korkunç bir felaketin ardından cumhurbaşkanının sıralamasındaki herkes de hayatını kaybedince, konut kent gelişimi alanındaki bakan Tom Kirkman, beklenmedik bir şekilde dünyanın en büyük ülkelerinden birinin başkanı olur.

14 Ekim 2011'de 140 milyon insan aniden ortadan kaybolduğu "Ani Ayrılma" adlı küresel bir olay yaşandı. New York'taki Mapleton kasabasında yaklaşık 150 kişi kayboldu ve hayatta kalanlar büyük kayıplarla baş etmek ve yeni koşullarda nasıl yaşayacaklarını öğrenmek zorunda.

Genç bir kız zombiye dönüşür, ama insanları öldürmek istemez. İhtiyacı olan beyinleri elde etmek için, yerel bir ameliyathane görevlisi ile çalışabileceği bir iş bulur. Daha sonra, yediği her beyinle birlikte o ölen insanların anılarına sahip olduğunu keşfeder.

Bir polis memurunun birden fazla zorlukla karşı karşıya olduğunu söylemek hiçbir şey demek değildir. Ama belki de en unutulmaz olanı bir çocuğa söz vermektir. Şimdi, James Gordon o sözü tutmak zorunda. Onun görevi genç Bruce'un anne ve babasını kimin öldürdüğünü öğrenmek.

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