He has traveled to every city, every town and every outpost in the United States, Mexico and Canada, and has found no one. As he returns to his hometown of Tucson, Phil comes to the realization that he is almost certainly the last living being on the face of the earth.
Phil is outcast after everyone finds out about him telling the new women his wife is dead and they are alone and trying to get up to some hanky panky. Carol has an issue with the new women for trying to steal her man, and there is unrest in the small community. Phil realizes he is a liar.
After Carol accidentally kills Gordan, a new addition to the Tuscon Crew, her and Phil try to find a way to ease themselves back into the group; Carol fakes Phil's death.
Phil and Todd rejuvenate their old friendship from Tuscon after doing time together; Phil and Phil 2's growing tension between each other over Carol reaches its tipping point.
When Erica claims she's pregnant to Phil 2 right before he is about to leave Malibu, he has to choose between his unborn child or a higher chance of survival by himself.
Along with most human life, the virus wiped out normal traditions and holidays. As Christmas approaches, Carol spearheads a “Secret Santa” gift exchange to spread some festive cheer.
Phil is diagnosed with appendicitis. Someone in the group has to step up to execute the surgery. Melissa has to deal with Tom's refusal of her proposal. Mike makes a decision about returning to earth.
Tandy sets up a unique alarm system in the house, but Melissa has already put her own safety precautions in place. The whole group decides to enjoy a change in scenery.
The search for a new home isn't easy for the group, especially when someone may be deliberately trying to stop them. Meanwhile, the love triangle between Todd, Gail and Melissa starts losing steam.
Carol will stop at nothing to get the perfect family photo. In the meantime, Melissa has her own mission, Lewis looks for a new hobby and Gail ends up in a scary situation.
After being locked up for her own safety, Melissa plays hurtful mind games with the group. Meanwhile, Todd and the group explore medications that might help her, and Lewis goes on a new solo adventure.
Tandy and Gail face off in a major disagreement, on which the whole group must weigh in, and Carol is forced to choose a side. Meanwhile, Melissa, Todd and Erica each have major milestone moments.
Tandy devises an escape plan to get away from Pamela and back to Carol and the others. Meanwhile, the rest of the gang encounters a castaway, Glenn, who has been stranded on an island for years.
Pamela tries desperately to redeem herself with everyone, as the gang finally reaches Mexico. Meanwhile, Todd is disappointed that Zihuatanejo is not the paradise of which he'd dreamed.
The gang moves into an old mansion; Carol forces Tandy to put down his new toys so they can baby-proof the giant estate; Melissa worries about Todd's health; Gail and Erica can't figure out why Dawn won't stop crying.
Todd asks Tandy for parenting advice when he notices that Jasper is acting more reckless than usual. Meanwhile, Carol and Erica realize that Jasper may be the only potential suitor for their babies and begin vying for his attention.
Tandy and Todd introduce newcomer Karl (guest star Fred Armisen) to the rest of the gang. Meanwhile, the group searches for Jasper, who has gone missing.
After the graveyard incident, Tandy and Todd try to convince the rest of the gang that something is majorly wrong with Karl and something needs to be done. Meanwhile, Jasper is still missing.
Tandy tries being a helpful, responsible adult in order to finally win Gail's praise. Meanwhile, Todd is furious with Melissa for keeping him away from Jasper.
While Todd butts heads with Erica, Melissa is determined to form a strong female friendship with her. Meanwhile, Carol grows suspicious that a new stranger could be living nearby.
Tandy wakes up to a shocking discovery that is positive for everyone in the group, but it throws Todd into a spiral. Meanwhile, Todd and Erica share an emotional roller coaster.
A thermal heat detector reveals a potential sign of life outside of the Zihuatanejo village, but Tandy doesn't want the group to split up to go investigate. Meanwhile, Todd and Erica have trouble seeing eye-to-eye.
The gang ventures out in search of what they think could be a new sign of life, but are surprised at what they actually find. Meanwhile, Todd makes a few morbid discoveries of his own back at the mansion.